CXCR3 antibody (AA 1-368)

Catalog No. ABIN3030511

Product Details anti-CXCR3 Antibody

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Binding Specificity: AA 1-368

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 1-368) was used as the immunogen for this CXCR3 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the CXCR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the CXCR3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for CXCR3

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Alternative Name: CXCR3 (CXCR3 Products)

Synonyms: CD182 antibody, CD183 antibody, CKR-L2 antibody, CMKAR3 antibody, GPR9 antibody, IP10-R antibody, Mig-R antibody, MigR antibody, Cd183 antibody, Cmkar3 antibody, CXCR3 antibody, cxcr3 antibody, Gpr9 antibody, CXC-R3 antibody, CXCR-3 antibody, zgc:92301 antibody, sb:eu378 antibody, C-X-C motif chemokine receptor 3 antibody, chemokine (C-X-C motif) receptor 3 antibody, chemokine (C-X-C motif) receptor 3, tandem duplicate 2 antibody, chemokine (C-X-C motif) receptor 3, tandem duplicate 1 antibody, CXCR3 antibody, Cxcr3 antibody, cxcr3 antibody, cxcr3.2 antibody, cxcr3.1 antibody

Background: CXCR3 is a Galphai protein-coupled receptor in the CXC chemokine receptor family. Other names for CXCR3 are G protein-coupled receptor 9 (GPR9) and CD183. CXCR3 is expressed on malignant B cells from chronic lymphoproliferative disorders, particularly in patients with CLL, and represents a fully functional receptor involved in chemotaxis of malignant B lymphocytes. It is found that in the absence of known etiologic agents, CXCR3 represents a novel target for therapeutic interference early in type 1 diabetes. Signaling is associated with MG pathogenesis and CXCR3 may serve as novel drug targets to treat MG. CXCR3A and CXCR3B are involved in the chemotactic and vascular effects of CXCL4L1.

Gene ID: 2833