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Factor VIII antibody (Middle Region)

F8 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3030544
  • Target See all Factor VIII (F8) Antibodies
    Factor VIII (F8) (Coagulation Factor VIII (F8))
    Binding Specificity
    • 15
    • 15
    • 15
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 91
    • 58
    • 30
    • 17
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 88
    • 18
    • 3
    • 1
    Rabbit
    Clonality
    • 94
    • 16
    Polyclonal
    Conjugate
    • 45
    • 15
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This Factor VIII antibody is un-conjugated
    Application
    • 51
    • 39
    • 39
    • 38
    • 23
    • 11
    • 10
    • 10
    • 10
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Antigen affinity
    Immunogen
    An amino acid sequence from the middle region of human F8 (APVLQDFRSLNDSTN) was used as the immunogen for this Factor VIII antibody.
    Isotype
    IgG
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  • Application Notes
    The stated application concentrations are suggested starting amounts. Titration of the Factor VIII antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the Factor VIII antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    Factor VIII (F8) (Coagulation Factor VIII (F8))
    Alternative Name
    Factor VIII (F8 Products)
    Synonyms
    fb61d02 antibody, wu:fb61d02 antibody, Cf-8 antibody, Cf8 antibody, FVIII antibody, AHF antibody, DXS1253E antibody, F8B antibody, F8C antibody, HEMA antibody, coagulation factor VIIi antibody, coagulation factor VIII antibody, coagulation factor VIII, procoagulant component antibody, f7i antibody, F8 antibody
    Background
    Coagulation Factor VIII (FVIII) is an essential blood-clotting protein. By in situ hybridization, Tantravahi et al.(1986) concluded that the F8 gene is located in the proximal part of chromosome Xq28 with probes DX13 and St14 distally located. The F8 gene encodes coagulation Factor VIII, a large plasma glycoprotein that functions in the blood coagulation cascade as a cofactor for the F9a-dependent activation of F10. Factor VIII is activated proteolytically by a variety of coagulation enzymes, including thrombin(F2). It is tightly associated in the blood with VWF, which serves as a protective carrier protein for Factor VIII (Toole et al., 1984, Hoyer, 1994).
    UniProt
    P00451
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