POU2F1 antibody (AA 11-240)

Catalog No. ABIN3032296

Product Details anti-POU2F1 Antibody

Target: POU2F1 (POU Domain, Class 2, Transcription Factor 1 (POU2F1))

Binding Specificity: AA 11-240

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POU2F1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 11-240) was used as the immunogen for this Oct-1 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the Oct-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Oct-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for POU2F1

Target: POU2F1 (POU Domain, Class 2, Transcription Factor 1 (POU2F1))

Alternative Name: Oct-1 (POU2F1) (POU2F1 Products)

Synonyms: OCT1 antibody, OTF1 antibody, oct-1B antibody, POU2F1 antibody, 2810482H01Rik antibody, NF-A1 antibody, Oct-1 antibody, Oct1 antibody, Otf-1 antibody, Otf1 antibody, chOCT-1 antibody, oct-1 antibody, oct1 antibody, pou2f1r antibody, fc07d06 antibody, wu:fc07d06 antibody, zgc:158360 antibody, POU class 2 homeobox 1 antibody, POU domain, class 2, transcription factor 1 antibody, POU class 2 homeobox 1 S homeolog antibody, POU class 2 homeobox 1b antibody, POU2F1 antibody, Pou2f1 antibody, pou2f1.S antibody, pou2f1b antibody

Background: POU domain class 2 transcription factor 1, also known as OTF1 or Oct-1, is a protein that in humans is encoded by the POU2F1 gene. The transcription factor was among the first identified members of the POU transcription factor family. It has been found that the Oct-1 dimer formed on the palindromic OCT factor recognition element, or PORE (ATTTGAAATGCAAAT), could recruit the transcriptional coactivator OBF1 , whereas dimers formed on the consensus MORE (more PORE) (ATGCATATGCAT) or on MOREs from immunoglobulin heavy chain promoters (AT[G/A][C/A]ATATGCAA) failed to interact. POU domain proteins contain a bipartite DNA-binding domain divided by a flexible linker that enables them to adopt various monomer configurations on DNA.

Gene ID: 5451