PTGER1 antibody (C-Term)

Catalog No. ABIN3032349

Product Details anti-PTGER1 Antibody

Target: PTGER1 (Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGER1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human PGE Receptor EP1 subtype (AWEASSLRSSRHSGLSHF) was used as the immunogen for this PGE Receptor antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the PGE Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the PGE Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for PTGER1

Target: PTGER1 (Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1))

Alternative Name: PGE Receptor, EP1 Subtype (PTGER1 Products)

Synonyms: EP1 antibody, PTGER1 antibody, 42kDa antibody, Ptgerep1 antibody, prostaglandin E receptor 1 antibody, prostaglandin E receptor 1 (subtype EP1), 42kDa antibody, prostaglandin E receptor 1 (subtype EP1) antibody, PTGER1 antibody, Ptger1 antibody

Background: Prostaglandin E Receptor 1 is a 402 amino acid protein with a predicted molecular mass of 44KD and has the seven transmembrane-spanning domains common to all G protein-coupled receptors. The PTGER1 gene is mapped to chromosome 19p13.1. The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E (PGE). Through a phosphatidylinositol-calcium second messenger system, Gq proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.

UniProt: P34995