SERPINB2 antibody (AA 1-180)

Catalog No. ABIN3032547

Product Details anti-SERPINB2 Antibody

Target: SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))

Binding Specificity: AA 1-180

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 1-180) was used as the immunogen for this SERPINB2 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the SERPINB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the SERPINB2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for SERPINB2

Target: SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))

Alternative Name: SERPINB2 (SERPINB2 Products)

Synonyms: HsT1201 antibody, PAI antibody, PAI-2 antibody, PAI2 antibody, PLANH2 antibody, SERPINB2 antibody, Planh2 antibody, ovalbumin antibody, Pai2a antibody, serpin family B member 2 antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 2 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 2 antibody, SERPINB2 antibody, Serpinb2 antibody

Target Type: Amino Acid

Background: SERPINB2 is also known as PAI or PAI2. It is a coagulation factor that inactivates tPA and Urokinase. It is present in most cells, especially monocytes/macrophages. The protein exists in two forms, a 60- kDa extracellular glycosylated form and a 43- kDa intracellular form. It is present only at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosisduring pregnancy. The majority of expressed SERPINB2 remains unsecreted due to the presence of an inefficient internal signal peptide.

Gene ID: 5055

Pathways: Autophagy