GRIN2B antibody (pTyr1252)

Catalog No. ABIN303962

The Rabbit Polyclonal anti-GRIN2B antibody is suitable to detect GRIN2B in samples from Human, Rat, Mouse, Dog, Cow and Chicken. It has been validated for WB.

Quick Overview for GRIN2B antibody (pTyr1252) (ABIN303962)

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Reactivity: Human, Rat, Mouse, Dog, Cow, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIN2B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GRIN2B Antibody

Binding Specificity: pTyr1252

Specificity: Specific for ~180k NM DAR NR2B subunit protein phosphorylated at Tyr1252. Immunolabeling of the NMDA NR2B subunit band is blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide. Immunolabeling is also blocked by a,-phosphatase treatment. The antibody may also show some slight reactivity with Tyr 1246 of NR2A

Purification: Immunoaffinity purified

Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phosphoTyr1252 of the NR213 subunit of the rat NMDA receptor.

Application Details

Application Notes: Approved: WB (1:1000)

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 μLof 10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol.

Storage: -20 °C

Storage Comment: Short term: -20°C
Long term: -20°C.

Target Details for GRIN2B

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Alternative Name: GRIN2B / NMDAR2B / NR2B

Background: Name/Gene ID: GRIN2B
Subfamily: Glutamate receptor - ionotropic (NMDA receptor)
Family: Ion Channel

Synonyms: GRIN2B, GluN2B, GluR epsilon 2, NMDA receptor 2B, NMDAR2B, NR2B, NR3, MRD6, HNR3

Gene ID: 2904

UniProt: Q13224

Pathways: Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity