ZEB2 antibody (AA 1-200)

Catalog No. ABIN3042325

Product Details anti-ZEB2 Antibody

Target: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Binding Specificity: AA 1-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZEB2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Zinc finger E-box-binding homeobox 2(ZEB2) detection. Tested with WB in Human.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Zinc finger E-box-binding homeobox 2(ZEB2) detection. Tested with WB in Human.
Gene Name: zinc finger E-box binding homeobox 2
Protein Name: Zinc finger E-box-binding homeobox 2

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ZEB2 recombinant protein (Position: M1-P200). Human ZEB2 shares 92% amino acid (aa) sequence identity with mouse ZEB2.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for ZEB2 is approximately 0.2 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for ZEB2

Target: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Alternative Name: ZEB2 (ZEB2 Products)

Synonyms: ZFHX1B antibody, Zfhx1b antibody, HSPC082 antibody, SIP-1 antibody, SIP1 antibody, SMADIP1 antibody, 9130203F04Rik antibody, D130016B08Rik antibody, Zfx1b antibody, Zfxh1b antibody, mKIAA0569 antibody, XSip1 antibody, sip1 antibody, zfhx1b antibody, si:dkey-52o2.2 antibody, sip1a antibody, wu:fc92g08 antibody, sip1b antibody, zinc finger E-box binding homeobox 2 antibody, zinc finger E-box binding homeobox 2 S homeolog antibody, zinc finger homeobox protein antibody, zinc finger E-box binding homeobox 2a antibody, zinc finger E-box binding homeobox 2b antibody, ZEB2 antibody, Zeb2 antibody, zeb2.S antibody, zeb2 antibody, zeb2a antibody, zeb2b antibody

Background: ZEB2(Zinc finger E-box-binding homeobox2), also known as SIP1 or ZINC FINGER HOMEOBOX 1B(ZFHX1B), is a protein that in humans is encoded by the ZEB2 gene. The ZEB2 gene is a member of the ZEB1/Drosophila Zfh1 family of 2-handed zinc finger/homeodomain proteins and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs, the transducers of TGF-beta signaling, and interacts with the nucleosome remodeling and histone deacetylation(NURD) complex. By radiation hybrid analysis, this gene is mapped to 2q22. It has been found that synthesis of ZEB2 was upregulated following SNAI1 expression in human cell lines, and the expression of SNAI1 in epithelial cells can trigger an epithelial-mesenchyme transition.

Synonyms: FLJ42816 antibody|HSPC082 antibody|KIAA0569 antibody|SIP 1 antibody|SIP1 antibody|Smad-interacting protein 1 antibody|SMADIP 1 antibody|SMADIP1 antibody|ZEB 2 antibody|ZEB2 antibody|ZEB2_HUMAN antibody|Zfhx1b antibody|ZFHX1B protein antibody|Zfx1b antibody|Zinc finger E box binding protein 2 antibody|Zinc finger E-box-binding homeobox 2 antibody|Zinc finger homeobox 1b antibody|zinc finger homeobox protein 1 antibody|Zinc finger homeobox protein 1b antibody

Gene ID: 9839

UniProt: O60315

Pathways: Tube Formation