RAP1A antibody (C-Term)

Catalog No. ABIN3042496

Product Details anti-RAP1A Antibody

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Binding Specificity: AA 156-181, C-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAP1A antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Ras-related protein Rap-1A(RAP1A) detection. Tested with WB in Human,Rat.

Sequence: EIFYDLVRQI NRKTPVEKKK PKKKSC

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Ras-related protein Rap-1A(RAP1A) detection. Tested with WB in Human,Rat.
Gene Name: RAP1A, member of RAS oncogene family
Protein Name: Ras-related protein Rap-1A

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human RAP1A (156-181aa EIFYDLVRQINRKTPVEKKKPKKKSC), identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for RAP1A

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Alternative Name: RAP1A (RAP1A Products)

Synonyms: KREV-1 antibody, KREV1 antibody, RAP1 antibody, SMGP21 antibody, AI848598 antibody, G-22K antibody, Krev-1 antibody, Rap1 antibody, RAP-1A antibody, rap 1A antibody, wu:fc66g06 antibody, zgc:86676 antibody, krev-1 antibody, krev1 antibody, rap1 antibody, RAP1A, member of RAS oncogene family antibody, RAS-related protein 1a antibody, RAP1A, member of RAS oncogene family a antibody, RAP1A, member of RAS oncogene family L homeolog antibody, RAP1A antibody, Rap1a antibody, rap1aa antibody, rap1a.L antibody

Background: Ras-related protein Rap-1A is a protein that in humans is encoded by the RAP1A gene. This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. And it is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. Additionally, the encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.

Synonyms: C21KG antibody|G 22K antibody|G-22K antibody|GTP binding protein smg p21A antibody|GTP-binding protein smg p21A antibody|KREV 1 antibody|KREV1 antibody|OTTHUMP00000013741 antibody|RAP 1A antibody|RAP1 antibody|RAP1A antibody|RAP1A member of RAS oncogene family antibody|RAP1A_HUMAN antibody|Ras related protein Krev 1 antibody|Ras related protein Rap 1A antibody|RAS related protein RAP1A antibody|Ras-related protein Krev-1 antibody|Ras-related protein Rap-1A antibody|SMGP21 antibody

Gene ID: 5906

UniProt: P62834

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor