TNFAIP8L3 antibody (C-Term)

Catalog No. ABIN3042574

Product Details anti-TNFAIP8L3 Antibody

Target: TNFAIP8L3 (Tumor Necrosis Factor, alpha-Induced Protein 8-Like 3 (TNFAIP8L3))

Binding Specificity: AA 273-292, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFAIP8L3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Tumor necrosis factor alpha-induced protein 8-like protein 3(TNFAIP8L3) detection. Tested with WB, IHC-P in Human.

Sequence: RPNLKRICEG INKLLDEKVL

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Tumor necrosis factor alpha-induced protein 8-like protein 3(TNFAIP8L3) detection. Tested with WB, IHC-P in Human.
Gene Name: tumor necrosis factor, alpha-induced protein 8-like 3
Protein Name: Tumor necrosis factor alpha-induced protein 8-like protein 3

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TNFAIP8L3(273-292aa RPNLKRICEGINKLLDEKVL), different from the related mouse and rat sequences by two amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for TNFAIP8L3

Target: TNFAIP8L3 (Tumor Necrosis Factor, alpha-Induced Protein 8-Like 3 (TNFAIP8L3))

Alternative Name: TNFAIP8L3 (TNFAIP8L3 Products)

Synonyms: 9930029P06Rik antibody, Gm517 antibody, TNF alpha induced protein 8 like 3 antibody, tumor necrosis factor, alpha-induced protein 8-like 3 antibody, TNF alpha induced protein 8 like 3 S homeolog antibody, TNFAIP8L3 antibody, Tnfaip8l3 antibody, tnfaip8l3.S antibody

Background: TNFAIP8L3 belongs to the TNFAIP8 family. It acts as a negative mediator of apoptosis and may play a role in tumor progression. This gene suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

Synonyms: 9930029P06Rik antibody|FLJ41287 antibody|Gm517 antibody|MGC141255 antibody|RGD1311533 antibody|TNF alpha-induced protein 8-like protein 3 antibody|TNFAIP8-like protein 3 antibody|tnfaip8l3 antibody|TP8L3_HUMAN antibody|Tumor necrosis factor alpha-induced protein 8-like protein 3 antibody