PON1 antibody (Middle Region)

Catalog No. ABIN3042578

Product Details anti-PON1 Antibody

Target: PON1 (Paraoxonase 1 (PON1))

Binding Specificity: AA 186-201, Middle Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Serum paraoxonase/arylesterase 1(PON1) detection. Tested with WB in Human,Mouse,Rat.

Sequence: FLDPYLQSWE MYLGLA

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Serum paraoxonase/arylesterase 1(PON1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: paraoxonase 1
Protein Name: Serum paraoxonase/arylesterase 1

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human PON1(186-201aa FLDPYLQSWEMYLGLA), different from the related mouse and rat sequences by three amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for PON1

Target: PON1 (Paraoxonase 1 (PON1))

Alternative Name: PON1 (PON1 Products)

Synonyms: esa antibody, pon antibody, pon2 antibody, MGC53915 antibody, MGC89222 antibody, PON1 antibody, ESA antibody, MVCD5 antibody, PON antibody, Pon antibody, paraoxonase 2 antibody, paraoxonase 1 antibody, pon2 antibody, PON1 antibody, Pon1 antibody

Background: Serum paraoxonase/arylesterase 1(PON1), also known as aromatic esterase 1, is an enzyme that in humans is encoded by the PON1 gene. It is mapped to 7q21.3. This gene has esterase and more specifically paraoxonase activity. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1(paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein(HDL). The PON1 gene is activated by PPAR-gamma, which increases synthesis and release of paraoxonase 1 enzyme from the liver, reducing atherosclerosis.

Synonyms: A esterase 1 antibody|A-esterase 1 antibody|Aromatic esterase 1 antibody|Arylesterase 1 antibody|Arylesterase B type antibody|ESA antibody|Esterase A antibody|K 45 antibody|K-45 antibody|MVCD5 antibody|Paraoxonase 1 antibody|Paraoxonase antibody|Paraoxonase B type antibody|Paraoxonase, plasma antibody|Paraoxonase1 antibody|PON 1 antibody|PON antibody|PON1 antibody|PON1_HUMAN antibody|Serum aryldiakylphosphatase antibody|Serum aryldialkylphosphatase 1 antibody|Serum paraoxonase/arylesterase 1 antibody

UniProt: P27169