CD86 antibody (AA 24-329)

Catalog No. ABIN3042788

Product Details anti-CD86 Antibody

Target: CD86

Binding Specificity: AA 24-329

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD86 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for T-lymphocyte activation antigen CD86(CD86) detection. Tested with WB, FCM in Human.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for T-lymphocyte activation antigen CD86(CD86) detection. Tested with WB, FCM in Human.
Gene Name: CD86 Molecule
Protein Name: T-lymphocyte activation antigen CD86

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CD86 recombinant protein (Position: A24-F329). Human CD86 shares 50% amino acid (aa) sequence identity with mouse CD86.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for CD86 is approximately 0.25 ng/lane under reducing conditions.
Flow Cytometry: Concentration:1-3 μg/1x106 cells, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for CD86

Target: CD86

Alternative Name: CD86 (CD86 Products)

Synonyms: B7-2 antibody, B7.2 antibody, B70 antibody, CD28LG2 antibody, LAB72 antibody, B7 antibody, CLS1 antibody, Cd28l2 antibody, ETC-1 antibody, Ly-58 antibody, Ly58 antibody, MB7 antibody, MB7-2 antibody, TS/A-2 antibody, CD86 molecule antibody, CD86 antigen antibody, integrin subunit alpha 2b antibody, CD86 antibody, Cd86 antibody, Itga2b antibody

Background: Cluster of Differentiation 86 (also known as CD86 and B7-2) is a protein expressed on antigen-presenting cells that provides costimulatory signals necessary for T cell activation and survival. The CD86 gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. Using fluorescence in situ hybridization mapping, the CD86, like CD80, was mapped to human 3q21. The antigen presentation coactivators B71 and B72, which are important in other immune-mediated thyroid diseases, are important for lymphocytic infiltration and the immune response against thyroid carcinoma.

Synonyms: Activation B7 2 antigen antibody|Activation B7-2 antigen 3 antibody|Activation B7-2 antigen antibody|Activation B72 antigen antibody|B lymphocyte activation antigen B7 2 antibody|B lymphocyte activation antigen B72 antibody|B-lymphocyte activation antigen B7-2 2 antibody|B-lymphocyte activation antigen B7-2 antibody|B7 2 antibody|B7 2 antigen antibody|B7 antibody|B7-2 antibody|B7.2 antibody|B70 antibody|B72 antigen antibody|BU63 antibody|CD 86 antibody|CD28 antigen ligand 2 2 antibody|CD28 antigen ligand 2 antibody|Cd28l2 antibody|CD28LG2 antibody|CD86 antibody|CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) 1, 2 antibody|CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) antibody|CD86 antigen antibody|CD86 Molecule antibody|CD86_HUMAN antibody|CLS1 antibody|CTLA 4 counter receptor B7 2 antibody|CTLA 4 counter receptor B7.2 antibody|CTLA-4 counter-receptor B7.2 2, 3 antibody|CTLA-4 counter-receptor B7.2 antibody|CTLA4 counter receptor B72 antibody|Early T-cell costimulatory molecule 1 antibody|ETC-1 antibody|FUN 1 antibody|FUN-1 antibody|FUN1 antibody|LAB72 antibody|Ly-58 antibody|Ly58 antibody|MB7 antibody|MB7-2 antibody|Membrane glycoprotein antibody|MGC34413 antibody|T lymphocyte activation antigen CD86 antibody|T-lymphocyte activation antigen CD86 antibody|TS/A-2 antibody

Gene ID: 942

UniProt: P42081

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation