APLP2 antibody (C-Term)

Catalog No. ABIN3043130

Product Details anti-APLP2 Antibody

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Binding Specificity: AA 639-656, C-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APLP2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Amyloid-like protein 2(APLP2) detection. Tested with WB in Human,Mouse,Rat.

Sequence: EEKVINSKNK VDENMVID

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Amyloid-like protein 2(APLP2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: amyloid beta(A4) precursor-like protein 2
Protein Name: Amyloid-like protein 2(APLP-2)

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human APLP2(639-656aa EEKVINSKNKVDENMVID), different from the related rat and mouse sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for APLP2 is approximately 0.5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for APLP2

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Alternative Name: APLP2 (APLP2 Products)

Synonyms: HAI antibody, MT-SP1 antibody, MTSP1 antibody, PRSS14 antibody, SNC19 antibody, TADG15 antibody, TMPRSS14 antibody, APLP-2 antibody, APPH antibody, APPL2 antibody, CDEBP antibody, AI790698 antibody, Apph antibody, WALPLP2 antibody, aplp2 B antibody, APLP2 antibody, si:dkey-11k4.3 antibody, aplp2 A antibody, MGC86389 antibody, suppression of tumorigenicity 14 antibody, amyloid beta precursor like protein 2 antibody, amyloid beta (A4) precursor-like protein 2 antibody, amyloid beta (A4) precursor-like protein 2 S homeolog antibody, amyloid beta (A4) precursor-like protein 2 L homeolog antibody, ST14 antibody, APLP2 antibody, Aplp2 antibody, aplp2.S antibody, aplp2 antibody, aplp2.L antibody

Background: APLP2(Amyloid beta(A4) precursor-like protein 2), also known as CDEBP or SPERM MEMBRANE PROTEIN, is a protein that in humans is encoded by the APLP2 gene. The APLP2 gene is mapped on 11q24.3. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. APLP2 along with APLP1 are important modulators of glucose and insulin homeostasis. APLP2 associates with antigen presentation molecules like MHC class I molecules and regulates their surface expression by enhancing endocytosis.

Synonyms: amyloid beta(A4) precursor like protein 2 antibody|Amyloid like protein 2 antibody|Amyloid precursor protein homolog HSD 2 antibody|amyloid precursor protein homolog HSD2 antibody|Amyloid protein homolog antibody|Amyloid-like protein 2 antibody|APLP-2 antibody|Aplp2 antibody|APLP2_HUMAN antibody|APPH antibody|APPL2 antibody|CDEBP antibody|CDEI box binding protein antibody|CDEI box-binding protein antibody

UniProt: Q06481

Pathways: EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour