HRPT2 antibody (AA 119-520)
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- Target See all HRPT2 (CDC73) Antibodies
- HRPT2 (CDC73) (Parafibromin (CDC73))
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Binding Specificity
- AA 119-520
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HRPT2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit IgG polyclonal antibody for Parafibromin(CDC73) detection. Tested with WB in Human.
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for Parafibromin(CDC73) detection. Tested with WB in Human.
Gene Name: cell division cycle 73
Protein Name: Parafibromin - Purification
- Immunogen affinity purified.
- Immunogen
- E.coli-derived human HRPT2 recombinant protein (Position: Q119-R520). Human HRPT2 shares 100% and 99.8% amino acid (aa) sequence identity with mouse and rat HRPT2, respectively.
- Isotype
- IgG
- Top Product
- Discover our top product CDC73 Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- HRPT2 (CDC73) (Parafibromin (CDC73))
- Alternative Name
- CDC73 (CDC73 Products)
- Synonyms
- C1orf28 antibody, HPTJT antibody, HRPT2 antibody, HYX antibody, 8430414L16Rik antibody, BC027756 antibody, C130030P16Rik antibody, C81219 antibody, Hrpt2 antibody, hrpt2 antibody, zgc:63956 antibody, MGC108428 antibody, cdc73 antibody, LOC100222932 antibody, cell division cycle 73 antibody, cell division cycle 73, Paf1/RNA polymerase II complex component antibody, cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) antibody, parafibromin antibody, cell division cycle 73 S homeolog antibody, CDC73 antibody, Cdc73 antibody, cdc73 antibody, Tsp_03925 antibody, Tsp_04052 antibody, Tsp_04125 antibody, cdc73.S antibody
- Background
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Cell division cycle 73, also known as HRPT2, is a protein which in humans is encoded by the CDC73 gene. This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. And this protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
Synonyms: C1orf28 antibody|CDC 73 antibody|Cdc73 antibody|CDC73_HUMAN antibody|Cell division cycle 73 antibody|Cell division cycle 73 Paf1/RNA polymerase II complex component homolog antibody| Cell division cycle protein 73 homolog antibody|FLJ23316 antibody|HPT JT antibody|HPTJT antibody|HRPT 2 antibody|Hyperparathyroidism 2 (with jaw tumor) antibody| Hyperparathyroidism 2 antibody|Hyperparathyroidism 2 protein antibody|HYX antibody| Parafibromin antibody - Gene ID
- 79577
- UniProt
- Q6P1J9
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
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