NR5A2 + LRH1 antibody (AA 44-237)

Catalog No. ABIN3043579

Product Details anti-NR5A2 + LRH1 Antibody

Target: NR5A2 + LRH1 (NR5A2) (Nuclear Receptor Subfamily 5, Group A, Member 2 (NR5A2))

Binding Specificity: AA 44-237

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR5A2 + LRH1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Nuclear receptor subfamily 5 group A member 2(NR5A2) detection. Tested with WB in Human.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Nuclear receptor subfamily 5 group A member 2(NR5A2) detection. Tested with WB in Human.
Gene Name: nuclear receptor subfamily 5, group A, member 2
Protein Name: Nuclear receptor subfamily 5 group A member 2

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NR5A2 recombinant protein (Position: K44-R237). Human NR5A2 shares 95% amino acid (aa) sequence identity with both mouse and rat NR5A2.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for NR5A2 is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-NR5A2 + LRH1 antibody (ABIN3043579)

Zhao, Wen, Zheng, Sun, Sun, Ni: "Action mechanism of Zuo Gui Yin Decoction's promotion on estradiol production in rats during the peri-menopausal period." in: Journal of ethnopharmacology, Vol. 134, Issue 1, pp. 122-9, (2011) (PubMed).

Target Details for NR5A2 + LRH1

Target: NR5A2 + LRH1 (NR5A2) (Nuclear Receptor Subfamily 5, Group A, Member 2 (NR5A2))

Alternative Name: NR5A2 (NR5A2 Products)

Synonyms: xff1rashort antibody, NR5A2 antibody, b1f antibody, b1f2 antibody, cpf antibody, ff1r antibody, ftf antibody, ftz-f1 antibody, ftz-f1beta antibody, hb1f antibody, hb1f-2 antibody, lrh-1 antibody, lrh1 antibody, xff1ra antibody, B1F antibody, B1F2 antibody, CPF antibody, FTF antibody, FTZ-F1 antibody, FTZ-F1beta antibody, LRH-1 antibody, LRH1 antibody, hB1F-2 antibody, xFF1rB antibody, AU020803 antibody, D1Ertd308e antibody, Ftf antibody, UF2-H3B antibody, Lrh-1 antibody, nuclear receptor subfamily 5 group A member 2 S homeolog antibody, nuclear receptor subfamily 5 group A member 2 antibody, nuclear receptor subfamily 5 group A member 2 L homeolog antibody, nuclear receptor subfamily 5, group A, member 2 antibody, nr5a2.S antibody, NR5A2 antibody, nr5a2 antibody, nr5a2.L antibody, Nr5a2 antibody

Background: NR5A2 (nuclear receptor subfamily 5, group A, member 2) also known as liver receptor homolog-1 (LRH-1) is a protein that in humans is encoded by the NR5A2 gene. LRH-1 is a member of the nuclear receptor family of intracellulartranscription factors. LRH-1 plays a critical role in the regulation of development,cholesterol transport, bile acid homeostasis andsteroidogenesis. LRH-1 is important for maintaining pluripotence of stem cells during embryonic development. Liver receptor homolog-1 has been shown to interact with the small heterodimer partner.

Synonyms: Alpha-1-fetoprotein transcription factor antibody|B1-binding factor antibody|B1F antibody|B1F2 antibody|CPF antibody|CYP7A promoter-binding factor antibody|FTF antibody|FTZ F1 antibody|FTZ F1beta antibody|FTZ-F1 antibody|FTZ-F1beta antibody|hB1F 2 antibody|HB1F antibody|hB1F-2 antibody|Hepatocytic transcription factor antibody|Liver receptor homolog 1 antibody|LRH-1 antibody|LRH1 antibody|Nr5a2 antibody|NR5A2_HUMAN antibody|Nuclear receptor subfamily 5 group A member 2 antibody

Gene ID: 2494

UniProt: O00482

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway