TRPV3 antibody (C-Term)

Catalog No. ABIN3044040

Product Details anti-TRPV3 Antibody

Target: TRPV3 (Transient Receptor Potential Cation Channel, Subfamily V, Member 3 (TRPV3))

Binding Specificity: AA 757-773, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPV3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Transient receptor potential cation channel subfamily V member 3(TRPV3) detection. Tested with WB in Human.

Sequence: RRTDFNKIQD SSRNNSK

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Transient receptor potential cation channel subfamily V member 3(TRPV3) detection. Tested with WB in Human.
Gene Name: transient receptor potential cation channel, subfamily V, member 3
Protein Name: Transient receptor potential cation channel subfamily V member 3

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TRPV3(757-773aa RRTDFNKIQDSSRNNSK), different from the related rat and mouse sequences by four amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for TRPV3 is approximately 0.5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TRPV3

Target: TRPV3 (Transient Receptor Potential Cation Channel, Subfamily V, Member 3 (TRPV3))

Alternative Name: TRPV3 (TRPV3 Products)

Synonyms: OLMS antibody, VRL3 antibody, 1110036I10Rik antibody, AI644701 antibody, Nh antibody, transient receptor potential cation channel subfamily V member 3 antibody, transient receptor potential cation channel, subfamily V, member 3 antibody, TRPV3 antibody, Trpv3 antibody

Background: TRPV3(Transient Receptor Potential Cation Channel Subfamily V Member 3), also known as VRL3, is a human gene encoding the protein of the same name. The TRPV3 protein belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. Peier et al.(2002) localized the TRPV3 gene to a BAC clone mapped to chromosome 17p13. They mapped the mouse gene to chromosome 11B4. Peier et al.(2002) stably expressed mouse Trpv3 in Chinese hamster ovary cells and assayed electrophysiologic activity by whole cell voltage-clamp techniques. They determined that Trpv3 is a cation-permeable channel activated by warm and hot temperatures. Xu et al.(2002) showed that increasing temperature from approximately 22 to 40 degrees Celsius in mammalian cells transfected with human TRPV3 elevated intracellular calcium by activating a nonselective cationic conductance.

Synonyms: 1110036I10Rik antibody|MGC124324 antibody|MGC124325 antibody|Transient receptor potential cation channel subfamily V member 3 antibody|TrpV3 antibody|Trpv3 heat sensitive channel antibody|TRPV3_HUMAN antibody|Vanilloid receptor 3 antibody|Vanilloid receptor like 3 antibody|Vanilloid receptor-like 3 antibody|vanilloid receptor-related osmotically activated channel protein antibody|VRL 3 antibody|VRL-3 antibody|VRL3 antibody