SLC6A4 antibody (N-Term)
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- Target See all SLC6A4 Antibodies
- SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))
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Binding Specificity
- AA 7-24, N-Term
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SLC6A4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for Sodium-dependent serotonin transporter(SLC6A4) detection. Tested with WB, IHC-P in Rat.
- Sequence
- NSQKVLSECK DREDCQEN
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for Sodium-dependent serotonin transporter(SLC6A4) detection. Tested with WB, IHC-P in Rat.
Gene Name: solute carrier family 6(neurotransmitter transporter, serotonin), member 5
Protein Name: Sodium-dependent serotonin transporter - Purification
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of rat SLC6A4(7-24aa NSQKVLSECKDREDCQEN), different from the related mouse sequence by one amino acid.
- Isotype
- IgG
- Top Product
- Discover our top product SLC6A4 Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Preservative
- Thimerosal (Merthiolate), Sodium azide
- Precaution of Use
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Expiry Date
- 12 months
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- Target
- SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))
- Alternative Name
- SLC6A4 (SLC6A4 Products)
- Synonyms
- 5-HTT antibody, 5-HTTLPR antibody, 5HTT antibody, HTT antibody, OCD1 antibody, SERT antibody, SERT1 antibody, hSERT antibody, AI323329 antibody, Htt antibody, Sert antibody, CG4545 antibody, DmSERT antibody, DmSerT antibody, Dmel\\CG4545 antibody, dSERT antibody, dSERT1 antibody, dSerT antibody, dSert antibody, dsert antibody, SLC6A4 antibody, solute carrier family 6 member 4 antibody, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 antibody, Serotonin transporter antibody, huntingtin antibody, solute carrier family 6 (neurotransmitter transporter), member 4b antibody, solute carrier family 6 (neurotransmitter transporter), member 4a antibody, SLC6A4 antibody, Slc6a4 antibody, SerT antibody, LOC100540532 antibody, slc6a4 antibody, slc6a4b antibody, slc6a4a antibody
- Background
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SLC6A4(Solute carrier family 6, member 4), also known as SERT(serotonin transporter), is a monoamine transporter protein. The SLC6A4 gene spans 31 kb and contains 14 exons. This protein integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. This transport of serotonin by the SERT protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is the target of many antidepressant medications, including those of the SSRI class. It is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, post-traumatic stress disorder and depression-susceptibility in people experiencing emotional trauma.
Synonyms: 5 HTT antibody|5 HTTLPR antibody|5 hydroxytryptamine(serotonin) transporter antibody|5 hydroxytryptamine transporter antibody|5HT transporter antibody|5HTT antibody|hSERT antibody|HTT antibody|Na+/Cl- dependent serotonin transporter antibody|OCD1 antibody|SC6A4_HUMAN antibody|Serotonin transporter 1 antibody|SERT antibody|SERT1 antibody|SLC6A4 antibody|Sodium dependent serotonin transporter antibody|Sodium-dependent serotonin transporter antibody|Solute carrier family 6(neurotransmitter transporter) member 4 antibody|solute carrier family 6(neurotransmitter transporter, serotonin), member 4 antibody|Solute carrier family 6 member 4 antibody - UniProt
- P31652
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