Vaccinia Virus antibody

Catalog No. ABIN305116

Product Details anti-Vaccinia Virus Antibody

Target: Vaccinia Virus (VACV) (Vaccina Virus (VACV))

Reactivity: Vaccinia Virus (VACV)

Host: Mouse

Clonality: Monoclonal

Conjugate: This Vaccinia Virus antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: Recognizes the Vaccinia virus, a large poxvirus. Poxviruses are DNA viruses that replicate in the cytoplasm of the host cell and therefore need a large genome to encode for the various proteins involved in DNA replication and transcription. Vaccinia virus infection is very mild and generally causes no symptoms in healthy individuals. Vaccinia infection initiates immune responses that also protects against smallpox, a much more severe disease with a high mortality rate. Vaccinia is best known for its use as a vaccine against smallpox, which was officially declared eradicated in 1980. There is some concern that smallpox might be re-introduced as a biological weapon, as such it might still pose a threat to humanity. Recognizes a 27kD protein in Western blotting of the following viruses: Vaccinia virus strain Elstree, Ectromelia virus strain K-1, Cowpox virus strain Grishak. It might also recognize the same protein in the Smallpox virus.

Purification: Affinity purified

Immunogen: Live dry smallpox vaccine.

Clone: TV43

Isotype: IgG2a

Application Details

Application Notes: Approved: ELISA, WB

Usage: Western Blot: LS-C58383 detects a band of approximately 27kD under non-reducing conditions.

Comment:

Target Species of Antibody: Vaccinia Virus

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Vaccinia Virus

Target: Vaccinia Virus (VACV) (Vaccina Virus (VACV))

Alternative Name: Vaccinia Virus (VACV Products)

Target Type: Virus