Bcl-2 antibody

Catalog No. ABIN306555

The Mouse Monoclonal anti-Bcl-2 antibody (Clone 10C4) (ABIN306555) specifically detects Bcl-2 in WB. The antibody is reactive with Mouse and Rat samples.

Quick Overview for Bcl-2 antibody (ABIN306555)

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reactivity: Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Bcl-2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 10C4

Product Details anti-Bcl-2 Antibody

Purpose: Mouse anti Mouse bcl-2

Cross-Reactivity: Human

Characteristics: The immunogen for the anti- mouse bcl - 2 was a synthetic peptide corresponding to amino acids 61 to 76 of the mouse bcl-2 sequence. Bcl-2 expression is associated with cell survival. The ratio of bcl-2 to other bcl-2 family members is believed to modulate apoptosis.

Purification: Protein A/G Chromatography

Isotype: IgG1

Application Details

Application Notes: Western Blots at 1-10 μg/mL

Restrictions: For Research Use only

Handling

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for Bcl-2

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Alternative Name: bcl-2

Background: Mbcl2, bcl2, mouse anti mouse bcl2

UniProt: P10415, P49950

Pathways: MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling