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Retinoblastoma Protein (Rb) antibody

Rb Protein Reactivity: Human, Mouse, Rat, Chicken, Mink Host: Mouse Monoclonal XZ91 unconjugated
Catalog No. ABIN306637
  • Target See all Retinoblastoma Protein (Rb) (Rb Protein) Antibodies
    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
    Reactivity
    • 131
    • 38
    • 25
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Chicken, Mink
    Host
    • 108
    • 24
    Mouse
    Clonality
    • 106
    • 26
    Monoclonal
    Conjugate
    • 70
    • 13
    • 10
    • 9
    • 9
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Retinoblastoma Protein (Rb) antibody is un-conjugated
    Application
    Please inquire
    Clone
    XZ91
    Isotype
    IgG1
    Top Product
    Discover our top product Rb Protein Primary Antibody
  • Restrictions
    For Research Use only
  • Target
    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
    Alternative Name
    Rb (Retinoblastoma) (Rb Protein Products)
    Background
    The immunogen for the anti-human retinoblastoma (Rb) was a recombinant protein corresponding to amino acids 393 to 572 of the human retinoblastoma sequence. Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors. Rb functions as a major cell cycle regulator by its ability to repress gene transcription by all three RNA polymerases. In its hypophosphorylated form, Rb binds to a subset of E2F containing complexes converting them to repressors preventing expression of E2F target genes. These complexes repress transcription via E2F binding elements in the promotersof cell cycle control genes, such as E2F-1, c-myc, and cdc2 genes. Synonyms: Retinoblastoma-associated protein, pRb, pp110, p105-Rb.
    UniProt
    P06400
    Pathways
    Mitotic G1-G1/S Phases
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