SPTLC1 antibody

Catalog No. ABIN307030

This Rabbit Polyclonal antibody specifically detects SPTLC1 in WB. It exhibits reactivity toward Human.

Quick Overview for SPTLC1 antibody (ABIN307030)

Target: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPTLC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SPTLC1 Antibody

Purpose: Rabbit anti Human Serine Palmitoyltransferase 1

Cross-Reactivity: Human

Characteristics: Sphingolipids play essential roles in various cellular events, including proliferation, differentiation, senescence, apoptosis, and inflammatory responses. Serine palmitoyltransferase (SPT) is the initial and rate-limiting enzyme in the de novo sphingolipid biosynthesis, and thus regulates the level of sphingolipids in cells. Immunohistochemical study revealed widespread distribution of the enzyme with most strong expression in brain and digestive tract. Two subunits, SPT1 and SPT2 at a stoichiometry of 1:1, are involved in the enzymatic activity of SPT.

Purification: Ammonium Sulfate Precipitation

Immunogen: Synthetic peptide derived from the human serine palmitoyltransferase enzyme.

Isotype: IgG

Application Details

Application Notes: Antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for SPTLC1

Target: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Alternative Name: Serine Palmitoyltransferase 1

Background: Long chain base biosynthesis protein 1, LCB-1, LCB1, Serine-palmitoyl-CoA transferase 1, SPT1, SPT 1, SPT-1

UniProt: O15269