PPP2CB antibody (AA 295-309)
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- Target See all PPP2CB Antibodies
- PPP2CB (Protein Phosphatase 2, Catalytic Subunit, beta Isozyme (PPP2CB))
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Binding Specificity
- AA 295-309
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Reactivity
- Human, Mouse, Rat, Pig, Zebrafish (Danio rerio), Dog, Horse, Monkey, Chicken, Xenopus laevis, Drosophila melanogaster, Rabbit, Cow, Hamster, Insect, Bat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PPP2CB antibody is un-conjugated
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Application
- Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP)
- Specificity
- Recognizes human PP2A, C subunit. Has been reported not to block phosphatase activity. Species cross-reactivity: bovine, mouse, rat, rabbit, Xenopus and yeast.
- Predicted Reactivity
- Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Dog, Bat, Bovine, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Lizard, Xenopus, Catfish, Salmon, Smelt, Stickleback, Pufferfish, Zebrafish, Seq squirt, Drosophila, Mosquito, Ant, Water flea, Slime mold, Nematode, Capsaspora (100%).
- Purification
- Protein G purified
- Immunogen
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Synthetic peptide (C-RGEPHVTRRTPDYFL) corresponding to aa295-309 of the 36kD catalytic subunit of human Protein Phosphatase 2A (PP2A). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Dog, Bat, Bovine, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Lizard, Xenopus, Catfish, Salmon, Smelt, Stickleback, Pufferfish, Zebrafish, Seq squirt, Drosophila, Mosquito, Ant, Water flea, Slime mold, Nematode, Capsaspora (100%).
Type of Immunogen: Synthetic peptide - Clone
- 1D6
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product PPP2CB Primary Antibody
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- Application Notes
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Approved: ICC (5 - 10 μg/mL), IP, WB (0.5 - 2 μg/mL)
Usage: Suitable for use in Western Blot, Immunoprecipitation and Immunocytochemistry. Western Blot: 0.5-2 μg/mL. Detects PP2A (36kD) in human A431 and in murine 3T3 RIPA cell lysates. Immunoprecipitation: 4 μg immunoprecipitated PP2A from 500 μg of A431 RIPA lysate. Immunocytochemistry: 5-10 μg/mL shows positive immunostaining for PP2A, C subunit in A431 fixed for 10 minutes with 4 % paraformaldehyde in PBS. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05 % sodium azide, 30 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- PPP2CB (Protein Phosphatase 2, Catalytic Subunit, beta Isozyme (PPP2CB))
- Alternative Name
- PP2CB / PPP2CB (PPP2CB Products)
- Synonyms
- pp2ac antibody, pp2ca antibody, rp-c antibody, AI115466 antibody, D8Ertd766e antibody, PP2Ac antibody, fb17h07 antibody, fc05c02 antibody, fk24a01 antibody, wu:fb17h07 antibody, wu:fc05c02 antibody, wu:fk24a01 antibody, zgc:55808 antibody, zgc:77172 antibody, PP2Abeta antibody, PP2CB antibody, Pp2a2 antibody, protein phosphatase 2 catalytic subunit alpha antibody, protein phosphatase 2, catalytic subunit, beta isozyme L homeolog antibody, protein phosphatase 2 catalytic subunit beta antibody, protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform antibody, protein phosphatase 2, catalytic subunit, beta isozyme antibody, ppp2ca antibody, ppp2cb.L antibody, PPP2CB antibody, Ppp2cb antibody, ppp2cb antibody
- Background
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Name/Gene ID: PPP2CB
Subfamily: PP2A
Family: Protein Phosphatase
Synonyms: PPP2CB, PP2Abeta, Protein phosphatase 2A beta, PP2CB, PP2A-beta, pp2a2 - Gene ID
- 5516
- UniProt
- P62714
- Pathways
- Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades
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