CNR2 antibody

Catalog No. ABIN317647

Product Details anti-CNR2 Antibody

Target: CNR2 (Cannabinoid Receptor 2 (CNR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificity: This antibody detects endogenous levels of Cannabinoid Receptor 2 (CB2) protein.(region surrounding Arg334)

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CNR2

Target: CNR2 (Cannabinoid Receptor 2 (CNR2))

Alternative Name: Cannabinoid Receptor 2 (CNR2 Products)

Synonyms: CNR2 antibody, CB2 antibody, cb2a antibody, cb2b antibody, CB-2 antibody, CX5 antibody, CB2C antibody, CNR2C antibody, CB2-R antibody, cannabinoid receptor 2 antibody, cannabinoid receptor 2 (macrophage) antibody, CNR2 antibody, cnr2 antibody, Cnr2 antibody

Background: The cannabinoid receptors (CB1 and CB2) are G protein-coupled receptors that inhibit adenylate cyclase activity in response to psychoactive cannabinoids.CB1 is expressed in brain tissue and, in low levels, in testis. CB2 is expressed only by cells of the immune system. The cannabinoid receptors mediate most of the cannabinoid-induced responses in a dose-dependent, stereoselective manner. This response system is thought to be involved in specific brain functions, such as nociception, control of movement, memory and neuroendocrine regulation, as well as having a possible role in brain development. In addition, CB1 may mediate the addictive behavior involved with the use of psychoactive cannabinoids, such as THC in marijuana.Synonyms: CB-2, CB2, CNR2, CX5, hCB2

Gene ID: 1269

NCBI Accession: NP_001832

UniProt: P34972