TACR2 antibody

Catalog No. ABIN317655

Product Details anti-TACR2 Antibody

Target: TACR2 (Tachykinin Receptor 2 (TACR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TACR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificity: This antibody detects endogenous levels of NK-2R protein.(region surrounding Pro340)

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TACR2

Target: TACR2 (Tachykinin Receptor 2 (TACR2))

Alternative Name: TACR2 / NK2R (TACR2 Products)

Synonyms: NK-2 antibody, TACR2 antibody, NK2R antibody, NKNAR antibody, SKR antibody, TAC2R antibody, Tac2r antibody, Nk2r antibody, Skr antibody, Rpa NK-2R antibody, NK-2R antibody, tachykinin receptor 2 antibody, TACR2 antibody, Tacr2 antibody

Background: This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. It has been reported to be expressed in trachea, lung, and gastrointestinal tract. ESTs have been isolated from human heart/melanocyte/uterus, prostate, and uterus libraries.Synonyms: NK-2 receptor, NK-2R, NKNAR, Neurokinin A receptor, Substance-K receptor, TAC2R, Tachykinin receptor 2

Molecular Weight: approx. 48 kDa

Gene ID: 6865

NCBI Accession: NP_001048

UniProt: P21452

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion