ZFP36L1 antibody
-
- Target See all ZFP36L1 Antibodies
- ZFP36L1 (ZFP36 Ring Finger Protein-Like 1 (ZFP36L1))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This ZFP36L1 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- TIS11B antibody detects endogenous levels of TIS11B protein.(region surrounding Asp88)
- Purification
- Affinity chromatography
- Top Product
- Discover our top product ZFP36L1 Primary Antibody
-
-
- Application Notes
-
ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Target
- ZFP36L1 (ZFP36 Ring Finger Protein-Like 1 (ZFP36L1))
- Alternative Name
- TIS11B / ZFP36L1 (ZFP36L1 Products)
- Synonyms
- ZFP36L1 antibody, berg36 antibody, brf1 antibody, c3h-2 antibody, cmg1 antibody, erf-1 antibody, erf1 antibody, rnf162b antibody, tis11b antibody, BRF1 antibody, Berg36 antibody, ERF-1 antibody, ERF1 antibody, RNF162B antibody, TIS11B antibody, cMG1 antibody, Brf1 antibody, TIS11b antibody, AW742437 antibody, AW743212 antibody, D530020L18Rik antibody, cb198 antibody, cb480 antibody, fk89d11 antibody, id:ibd1247 antibody, sb:cb198 antibody, sb:cb480 antibody, wu:fb80h11 antibody, wu:fb92f07 antibody, wu:fk89d11 antibody, zfp36l1 antibody, zfp36l2 antibody, zgc:153979 antibody, fc06f10 antibody, wu:fc06f10 antibody, zfp36l1l antibody, zgc:77882 antibody, ZFP36 ring finger protein-like 1 S homeolog antibody, ZFP36 ring finger protein like 1 antibody, zinc finger protein 36, C3H type-like 1 antibody, zinc finger protein 36, C3H type-like 1a antibody, BRF1, RNA polymerase III transcription initiation factor subunit antibody, transcription factor IIIB 90 kDa subunit antibody, zinc finger protein 36, C3H type-like 1b antibody, zfp36l1.S antibody, ZFP36L1 antibody, Zfp36l1 antibody, zfp36l1a antibody, BRF1 antibody, LOC100350146 antibody, zfp36l1b antibody
- Background
- TIS11B (tetradecanoyl phorbol acetate-inducible sequence 11b), also known as ZFP36L1, BRF1 (butyrate response factor 1), ERF1 (EGF response factor 1), cMG1, Berg36 or RNF162B, is a member of the tristetraprolin family. Tristetraprolin (TTP), or TIS11, is a zinc-binding protein encoded by the immediate-early response gene, Zfp-36. TIS11B, a relative of TTP, localizes to the nucleus and may function as a transcription factor involved in regulating the growth factor response. It is an evolutionarily conserved protein containing two C3H1-type zinc fingers and a repeating Cys-His motif. TIS11B is an mRNA binding protein and is known to interact with the 3'-untranslated region of VEGF mRNA, thereby decreasing its stability. This suggests that TIS11B is a potential target in antiangiogenic therapy. In addition, TIS11B may also be an important regulator of myogenesis, as its expression is upregulated during murine myoblast differentiation.Synonyms: BERG36, BRF1, Butyrate response factor 1, EGF-response factor 1, ERF-1, ERF1, RNF162B, Tetradecanoyl phorbol acetate-inducible sequence 11b
- Molecular Weight
- approx. 36 kDa
- Gene ID
- 677
- NCBI Accession
- NP_004917
- UniProt
- Q07352
-