SSTR1 antibody

Catalog No. ABIN317866

Product Details anti-SSTR1 Antibody

Target: SSTR1 (Somatostatin Receptor 1 (SSTR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSTR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificity: SSTR1 antibody detects endogenous levels of SSTR1 protein.(region surrounding asn48)

Purification: Affinity chromatography

Application Details

Application Notes: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SSTR1

Target: SSTR1 (Somatostatin Receptor 1 (SSTR1))

Alternative Name: SSTR1 (SSTR1 Products)

Synonyms: SSTR1 antibody, LOC100313735 antibody, SRIF-2 antibody, SS-1-R antibody, SS1-R antibody, SS1R antibody, Smstr-1 antibody, Smstr1 antibody, sst1 antibody, Gpcrrna antibody, somatostatin receptor 1 antibody, uncharacterized SSTR1 antibody, SSTR1 antibody, LOC100313735 antibody, Sstr1 antibody

Background: SSTRs (for somatostatin receptors) represent a family of G-protein-coupled receptors which mediate the diverse biological actions of somatostatin(SST). There are five distinct subtypes of SSTRs that bind two natural ligands, SST-14 and SST-28. SSTR2 gives rise to spliced variants, SSTR2A and 2B. SSTRs share common signaling pathways such as the ability to inhibit adenylyl cyclase via GTP binding proteins. Some of the subtypes are also coupled to tyrosine phosphatase (SSTR1,2), Ca2+ channels (SSTR2), Na+/H+ exchanger (SSTR1), PLA-2 (SSTR4), and MAP kinase (SSTR4). Individual target cells typically express more than one SSTR subtype and often all five isoforms. Subtypes of SSTR can form functional homo- and heterodimers.Synonyms: SRIF-2, SS-1-R, SS1-R, SS1R, Somatostatin receptor type 1

Molecular Weight: approx. 43 kDa

Gene ID: 6751

NCBI Accession: NP_001040

UniProt: P30872