SSTR4 antibody

Catalog No. ABIN317867

Product Details anti-SSTR4 Antibody

Target: SSTR4 (Somatostatin Receptor 4 (SSTR4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSTR4 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: SSTR4 antibody detects endogenous levels of SSTR4 protein.(region surrounding Gln194)

Purification: Affinity chromatography

Application Details

Application Notes: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SSTR4

Target: SSTR4 (Somatostatin Receptor 4 (SSTR4))

Alternative Name: SSTR4 (SSTR4 Products)

Synonyms: SS4R antibody, SSTR4 antibody, LOC100303655 antibody, SS-4-R antibody, SS4-R antibody, Smstr4 antibody, sst4 antibody, somatostatin receptor 4 antibody, SSTR4 antibody, Sstr4 antibody

Background: SSTRs (for somatostatin receptors) represent a family of G-protein-coupled receptors which mediate the diverse biological actions of somatostatin(SST). There are five distinct subtypes of SSTRs that bind two natural ligands, SST-14 and SST-28. SSTR2 gives rise to spliced variants, SSTR2A and 2B. SSTRs share common signaling pathways such as the ability to inhibit adenylyl cyclase via GTP binding proteins. Some of the subtypes are also coupled to tyrosine phosphatase (SSTR1,2), Ca2+ channels (SSTR2), Na+/H+ exchanger (SSTR1), PLA-2 (SSTR4), and MAP kinase (SSTR4). Individual target cells typically express more than one SSTR subtype and often all five isoforms. Subtypes of SSTR can form functional homo- and heterodimers.Synonyms: SS-4-R, SS4-R, SS4R, Somatostatin receptor type 4

Molecular Weight: approx. 42 kDa

Gene ID: 6754

NCBI Accession: NP_001043

UniProt: P31391

Pathways: cAMP Metabolic Process