Caspase 8 antibody (pSer347)

Catalog No. ABIN3181944

This Rabbit Polyclonal antibody specifically detects Caspase 8 in WB, IHC and ELISA. It exhibits reactivity toward Human and Rat.

Quick Overview for Caspase 8 antibody (pSer347) (ABIN3181944)

Target: Caspase 8 (CASP8)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Caspase 8 Antibody

Binding Specificity: pSer347

Specificity: Phospho-Caspase-8 (S347) Polyclonal Antibody detects endogenous levels of Caspase-8 protein only when phosphorylated at S347.

Characteristics: Rabbit Polyclonal to Phospho-Caspase-8 (S347).

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Caspase-8 around the phosphorylation site of S347.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for Caspase 8

Target: Caspase 8 (CASP8)

Alternative Name: Caspase-8

Molecular Weight: 55 kDa

Gene ID: 841

UniProt: Q14790

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades