Bcl-2 antibody (pThr74)

Catalog No. ABIN3182991

The Rabbit Polyclonal anti-Bcl-2 antibody (ABIN3182991) specifically detects Bcl-2 in IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for Bcl-2 antibody (pThr74) (ABIN3182991)

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Bcl-2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-Bcl-2 Antibody

Binding Specificity: pThr74

Specificity: Phospho-Bcl-2 (T74) Polyclonal Antibody detects endogenous levels of Bcl-2 protein only when phosphorylated at T74.

Characteristics: Rabbit Polyclonal to Phospho-Bcl-2 (T74).

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Bcl-2 around the phosphorylation site of T74.

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:300, ELISA 1:10000,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for Bcl-2

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Alternative Name: Bcl-2

Molecular Weight: 26 kDa

Gene ID: 596

UniProt: P10415

Pathways: MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling