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CD16 antibody

CD16 Reactivity: Human FACS, IHC (fro) Host: Rat Monoclonal YFC120-5 unconjugated

Catalog No. ABIN320001

Datasheet as PDF

Target See all CD16 Antibodies

CD16
Reactivity
128

20

20

20

16

9

8

8

7

4

2

2

2

2

2

2

2

1

1

1
Human
Host
111

28

5

1
Rat
Compatible Secondaries
Clonality
117

26

1
Monoclonal
Conjugate
53

17

12

11

6

6

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD16 antibody is un-conjugated
Application
115

29

26

25

24

21

21

17

6

5

3

3

3

2

2

1
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity

This antibody binds specifically to the leucocyte low affinity Fc receptor (Fc RIII), also known as CD16. It recognises a 50-70 kDa leucocyte surface antigen.

Purification

Affinity chromatography on Protein A.

Immunogen

Human neutrophils. Spleen cells from Lou rat fused with the rat myeloma cell line. Y3/Ag.1.2.3.

Clone

YFC120-5

Isotype

IgG2b

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anti-CD16 (CD16) antibody
CD16 Reactivity: Human FACS, IP, WB Host: Mouse Monoclonal MEM-154 unconjugated

anti-CD16 (CD16) antibody
CD16 Reactivity: Human, Pig, Non-Human Primate FACS Host: Mouse Monoclonal MEM-168 unconjugated

anti-CD16 (CD16) antibody
CD16 Reactivity: Human FACS, IP, WB, Func Host: Mouse Monoclonal MEM-154 unconjugated

anti-CD16 (CD16) antibody (Biotin)
CD16 Reactivity: Human FACS, IP, WB Host: Mouse Monoclonal MEM-154 Biotin

anti-CD16 (CD16) (AA 17-208) antibody
CD16 Reactivity: Human FACS, WB, IHC, ELISA, ICC, Neut Host: Mouse Monoclonal 2G10A9 unconjugated

anti-CD16 (CD16) antibody
CD16 Reactivity: Human, Non-Human Primate FACS, IP, Func, IHC (fro) Host: Mouse Monoclonal 3G8 unconjugated

anti-CD16 (CD16) antibody (PE-DyLight 594)
CD16 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal 3G8 PE-DyLight 594

anti-CD16 (CD16) antibody
CD16 Reactivity: Human FACS Host: Mouse Monoclonal GRM1 unconjugated

Application Notes

Flow Cytometry. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions

For Research Use only
Concentration

1.0 mg/mL

Buffer

PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid repeated freezing and thawing.

Storage

4 °C/-20 °C

Storage Comment

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target

CD16

Alternative Name

CD16 (CD16 Products)

Synonyms

Fcgr3 antibody, Fcgr3a antibody, CD16 antibody, FCGR3 antibody, FCGR3@ antibody, CD16b antibody, FCG3 antibody, FCR-10 antibody, FCRIII antibody, FCRIIIb antibody, FcRIII antibody, Fc fragment of IgG, low affinity IIa, receptor antibody, Fc fragment of IgG, low affinity IIIa, receptor (CD16a) antibody, Fc fragment of IgG receptor IIIb antibody, Fc fragment of IgG receptor IIIa antibody, Fc receptor, IgG, low affinity III antibody, Fc-gamma RIII antibody, Fcgr2a antibody, FCGR3A antibody, FCGR3B antibody, Fcgr3 antibody, FCGR3 antibody

Background

The antigen is expressed by neutrophils, NK cells, K cells and a subpopulation of macrophages.Synonyms: CD16A, FCG3, FCGR3, FCGR3A, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FcR-10, FcRIII, FcRIIIa, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A

Gene ID

2214

NCBI Accession

NP_000560

UniProt

P08637

Pathways

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process