Factor V Heavy Chain antibody
Reactivity: Human
ELISA, IHC, RIA
Host: Mouse
Monoclonal
B10
unconjugated
-
- Target
- Factor V Heavy Chain
- Reactivity
- Human
- Host
- Mouse
- Clonality
- Monoclonal
- Application
- ELISA, Immunohistochemistry (IHC), Radioimmunoassay (RIA)
- Specificity
- Reacts with human thrombin-cleaved Factor V Heavy Chain. KD = 1.15 x 10.-10Mol/L.
- Purification
- Purified (protein G)
- Immunogen
- Purified human Factor V.
- Clone
- B10
- Isotype
- IgG1
-
- Application Notes
- Working dilution: Optimal dilution should be determined by the end user.
- Restrictions
- For Research Use only
-
- Buffer
- PBS, pH 7.4.
- Handling Advice
- Dilute in PBS or medium that is identical to that used in the assay system.
- Storage
- -20 °C/-80 °C
- Storage Comment
- Stable for at least one year at -20°C to -70°C. Avoid multiple freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- Factor V Heavy Chain
- Background
-
Factor V is an essential cofactor of the blood coagulation cascade and a central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions.
Coagulation factor V Activated protein C cofactor Proaccelerin, labile factor Coagulation factor V heavy chain FVL PCCF THPH2 RPRGL1 Gene name : F5 - Gene ID
- 2153
- UniProt
- P12259
-
You are here:
