HLAG antibody (Biotin)

Catalog No. ABIN3200974

The Mouse Monoclonal anti-HLAG antibody is suitable to detect HLAG in samples from Human. It has been validated for ELISA, FACS, IHC (fro) and Func.

Quick Overview for HLAG antibody (Biotin) (ABIN3200974)

Target: HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HLAG antibody is conjugated to Biotin

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: 87G

Product Details anti-HLAG Antibody (Biotin)

Specificity: Reacts with both membrane-bound and soluble forms of human HLA-G (HLA-G1 and HLA-G5)

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Blocks interaction of HLA-G with inhibitory receptors. Does not cross-react with mouse, rat protein.

Purification: Purified

Immunogen: HLA-B27 transgenic mice were imunized with H-2 identical murine cells transfected with and expressing genes encoding HLA-G and human beta2-microglobulin.

Isotype: IgG2a

Application Details

Application Notes:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- FC: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, Sodium azide 15 mM

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for HLAG

Target: HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))

Alternative Name: HLA-G

Gene ID: 3135

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response