BACE1 antibody
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- Target See all BACE1 Antibodies
- BACE1 (Beta-secretase 1 (BACE1))
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This BACE1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunoprecipitation (IP), Neutralization (Neut)
- Specificity
- Recognizes human BACE-1 ectodomain. Species cross-reactivity: Mouse.
- Purification
- Protein G purified
- Immunogen
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NS0-derived rhBACE-1 ectodomain.
Type of Immunogen: Recombinant protein - Isotype
- IgG1
- Top Product
- Discover our top product BACE1 Primary Antibody
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anti-Beta-secretase 1 (BACE1) (AA 112-324) antibody
BACE1 Reactivity: Human, Mouse, Rat WB, ELISA, ICC, FACS Host: Mouse Monoclonal 3C1C3 unconjugated
anti-Beta-secretase 1 (BACE1) (AA 22-501) antibodyBACE1 Reactivity: Human WB, ELISA, IHC (p), PLA Host: Mouse Monoclonal 2C1 unconjugated
anti-Beta-secretase 1 (BACE1) (N-Term) antibodyBACE1 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (AA 401-501) antibodyBACE1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), ICC, FACS, IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (AA 38-70), (N-Term) antibodyBACE1 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB16874 unconjugated
anti-Beta-secretase 1 (BACE1) (AA 22-322) antibodyBACE1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (AA 46-155) antibodyBACE1 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (C-Term) antibodyBACE1 Reactivity: Human, Monkey IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (AA 72-121) antibodyBACE1 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Monkey, Pig, Bat, Hamster WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (AA 170-428) antibodyBACE1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
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Approved: ELISA, IP, Neut, WB
Usage: Suitable for use in ELISA, Immunoprecipitation/ Western Blot and Neutralization. The enzyme was then assayed with a peptide substrate. 50 % of the proteolytic activity was inhibited by the antibody at 10 μg/mL (IC50) under conditions in which the enzyme was present at 10 μg/mL and the substrate concentration was 10uM. Considering the molecular masses of the enzyme (75kD) and the antibody (150kD), IC50 was achieved at ~0.5:1 Molar ratio of the antibody to the enzyme. Did not inhibit rhCathepsin D activity under the same conditions. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Sterile PBS
- Concentration
- Lot specific
- Buffer
- Lyophilized, PBS, pH 7.4, 5 % trehalose
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C,-20 °C
- Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- BACE1 (Beta-secretase 1 (BACE1))
- Alternative Name
- BACE1 / BACE (BACE1 Products)
- Synonyms
- ASP2 antibody, BACE antibody, HSPC104 antibody, C76936 antibody, Bace antibody, MGC145931 antibody, BACE1 antibody, zgc:77409 antibody, beta-secretase 1 antibody, beta-site APP cleaving enzyme 1 antibody, beta-site APP-cleaving enzyme 1 antibody, BACE1 antibody, Bace1 antibody, bace1 antibody
- Background
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Name/Gene ID: BACE1
Subfamily: Aspartic A1
Family: Protease
Synonyms: BACE1, APP beta-secretase, Asp 2, ASP2, Aspartyl protease 2, Aspartylprotease 2, Beta-secretase, Beta-site APP-cleaving enzyme, BACE, HSPC104, KIAA1149, B-Secretase, Beta-secretase 1, Memapsin-2 - Gene ID
- 23621
- UniProt
- P56817
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