IL-1 beta antibody

Catalog No. ABIN326595

The Mouse Monoclonal anti-IL-1 beta antibody (Clone ID4) (ABIN326595) specifically detects IL-1 beta in IHC, ELISA, FACS and IHC (fro). The antibody is reactive with Sheep, Cow and Goat samples.

Quick Overview for IL-1 beta antibody (ABIN326595)

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reactivity: Sheep, Cow, Goat

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-1 beta antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: ID4

Product Details anti-IL-1 beta Antibody

Specificity: Recognizes sheep interleukin-1 Beta and shows no cross-reactivity with sheep IL-6, IL-8, TNF alpha or MCP-1. The antibody may be used in combination with AHP423 in ELISA assays and demonstrates partial neutralizing activity. Species cross-reactivity: goat, bovine IL-1 Beta.

Purification: Purified

Immunogen: Recombinant ovine IL-1 Beta.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, Flo (1:10), IHC, IHC-Fr

Usage: Suitable for use in ELISA, Flow Cytometry and Immunohistochemistry. Flow Cytometry: 1:10. Use 10 μL to label 1 x10⁶ in 100 μL. Membrane permeabilization is required. Immunohistochemistry: Frozen sections.

Comment:

Target Species of Antibody: Sheep

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Alternative Name: IL1B

Background: Name/Gene ID: IL1B
Family: IL-1

Synonyms: IL1B, IL-1B, IL-1 beta, IL1-BETA, Preinterleukin 1 beta, Pro-interleukin-1-beta, Catabolin, IL-1, IL1F2, Interleukin 1, beta, Interleukin-1 beta

Gene ID: 3553

UniProt: P01584

Pathways: NF-kappaB Signaling, Interferon-gamma Pathway, TLR Signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome