Amylin/DAP antibody
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- Target See all Amylin/DAP (IAPP) Antibodies
- Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))
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Reactivity
- Human
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Host
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Chicken
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Clonality
- Polyclonal
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Conjugate
- This Amylin/DAP antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Characteristics
- Expected / apparent Molecular Weight of the Antigene: 4 kDa
- Purification
- affinity purified
- Immunogen
- synthetic peptide based on human IAPP sequence: K-C-N-T-A-T-C-A-T-Q-R-L-A-N-F-L-V-H-S-S-N-N-F-G-A-I-L-S-S-T-N-V-G-S-N-T-Y
- Isotype
- IgY
- Top Product
- Discover our top product IAPP Primary Antibody
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- Application Notes
- Recommended Dilution: 1 : 1000 (WB), 1 : 1000 (ELISA).
- Comment
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antibody is recognizing trimer, dimer and monomer human IAPP
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS pH 8.0 + 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
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Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
Make aliquots to avoid repreated freeze-thaw cycles and working with a stock. - Storage
- 4 °C
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- Target
- Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))
- Alternative Name
- IAPP (IAPP Products)
- Synonyms
- DAP antibody, IAP antibody, LOC100230121 antibody, Amylin antibody, islet amyloid polypeptide antibody, IAPP antibody, Iapp antibody
- Background
- Amylin, or Islet Amyloid Polypeptide (IAPP) P10997, is a 37-residue peptide hormone secreted by pancreatic beta-cells at the same time as insulin (in a roughly 1:100 amylin:insulin ratio). Islet, or insulinoma, almyloid polypeptide (IAPP, or amylin) is commonly found in pancreatic islets of patients suffering diabetes mellitus type 2, or harboring an insulinoma. While the association of amylin with the development of type 2 diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzherimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the deleopment of type 2 diabetes.
- Molecular Weight
- 4 kDa
- Pathways
- Hormone Activity, Feeding Behaviour
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