KPNA4 antibody (AA 509-521)

Catalog No. ABIN337020

The Goat Polyclonal anti-KPNA4 antibody (ABIN337020) specifically detects KPNA4 in WB, ELISA, IHC and IHC (p). The antibody is reactive with Human, Cow, Dog, Horse, Rabbit, Bat, Hamster and Monkey samples.

Quick Overview for KPNA4 antibody (AA 509-521) (ABIN337020)

Target: KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

Reactivity: Human, Cow, Dog, Horse, Rabbit, Bat, Hamster, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This KPNA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-KPNA4 Antibody

Binding Specificity: AA 509-521

Specificity: Human KPNA4.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Bovine, Dog, Bat, Hamster, Elephant, Panda, Horse, Rabbit, Opossum (100%) Mouse, Rat, Turkey, Chicken, Platypus, Xenopus (92%) Zebrafish (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-NSSANVPTEGFQF from the C-terminus of human KPNA4 (NP_002259.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Bovine, Dog, Bat, Hamster, Elephant, Panda, Horse, Rabbit, Opossum (100%), Mouse, Rat, Turkey, Chicken, Platypus, Xenopus (92%), Zebrafish (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA, WB (0.2 - 1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for KPNA4

Target: KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

Alternative Name: QIP1 / KPNA4

Background: Name/Gene ID: KPNA4

Synonyms: KPNA4, Importin subunit alpha-4, Importin alpha Q1, Karyopherin subunit alpha-4, SRP3, IPOA3, QIP1

Gene ID: 3840

NCBI Accession: NP_002259

Pathways: Protein targeting to Nucleus