PDE11A antibody (AA 455-468)

Catalog No. ABIN337393

Product Details anti-PDE11A Antibody

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Binding Specificity: AA 455-468

Reactivity: Human, Dog, Cow, Bat, Pig, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This PDE11A antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human PDE11A. This antibody is expected to recognise all four reported isoforms (NP_058649.3 , NP_001070665.1, NP_001070826.1, NP_001070664.1).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Panda, Bovine, Dog, Bat, Pig (100%) Mouse, Rat, Hamster, Horse, Rabbit, Opossum (93%) Xenopus, Stickleback, Pufferfish, Zebrafish (86%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-NSFKESMEKSSYSD from an internal region of human PDE11A (NP_058649.3 , NP_001070665.1, NP_001070826.1, NP_001070664.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Panda, Bovine, Dog, Bat, Pig (100%), Mouse, Rat, Hamster, Horse, Rabbit, Opossum (93%), Xenopus, Stickleback, Pufferfish, Zebrafish (86%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (10 μg/mL), Peptide-ELISA (1:2000), WB (0.5 - 1.5 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for PDE11A

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Alternative Name: PDE11A (PDE11A Products)

Synonyms: PPNAD2 antibody, 6330414F14Rik antibody, A630086N24Rik antibody, Gm350 antibody, PDE11A1 antibody, si:ch211-222f23.5 antibody, PDE11A antibody, ppnad2 antibody, Pde11a antibody, phosphodiesterase 11A antibody, phosphodiesterase 11a antibody, dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A antibody, PDE11A antibody, Pde11a antibody, pde11a antibody, LOC100470038 antibody

Background: Name/Gene ID: PDE11A
Subfamily: PDE - cAMP/cGMP dual-specific
Family: Phosphodiesterase

Synonyms: PDE11A, Pde11, PDE11A4, PDE11A1, PPNAD2, PDE11A2, PDE11A3, Phosphodiesterase 11A

Gene ID: 50940

NCBI Accession: NP_058649, NP_001070665, NP_001070826, NP_001070664

UniProt: Q9HCR9

Pathways: cAMP Metabolic Process