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PDE11A antibody (N-Term)

PDE11A Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5537471
  • Target See all PDE11A Antibodies
    PDE11A (phosphodiesterase 11A (PDE11A))
    Binding Specificity
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 34-63, N-Term
    Reactivity
    • 32
    • 24
    • 21
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 34
    • 1
    Rabbit
    Clonality
    • 35
    Polyclonal
    Conjugate
    • 16
    • 8
    • 7
    • 2
    • 1
    • 1
    This PDE11A antibody is un-conjugated
    Application
    • 29
    • 27
    • 19
    • 15
    • 12
    • 10
    • 9
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PDE11A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-63 amino acids from the N-terminal region of human PDE11A.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PDE11A Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    PDE11A (phosphodiesterase 11A (PDE11A))
    Alternative Name
    PDE11A (PDE11A Products)
    Synonyms
    PPNAD2 antibody, 6330414F14Rik antibody, A630086N24Rik antibody, Gm350 antibody, PDE11A1 antibody, si:ch211-222f23.5 antibody, PDE11A antibody, ppnad2 antibody, Pde11a antibody, phosphodiesterase 11A antibody, phosphodiesterase 11a antibody, dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A antibody, PDE11A antibody, Pde11a antibody, pde11a antibody, LOC100470038 antibody
    Background
    The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    105 kDa
    Gene ID
    50940
    UniProt
    Q9HCR9
    Pathways
    cAMP Metabolic Process
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