BIRC7 antibody (AA 264-280)

Catalog No. ABIN341778

Product Details anti-BIRC7 Antibody

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Binding Specificity: AA 264-280

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIRC7 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Recognizes human Livin, a novel member of the IAP protein family. Livin contains a single baculoviral IAP repeat domain and a RING finger domain and has two isoforms, Livin-a and Livin-~. Transfection of Livin in cells results in protection from apoptosis induced by FADD, Bax, RIP, RIP3, and DR6. Livin interacts directly with caspase-3, -7, and -9 and inhibits the activation of caspase-9 induced by Apaf-1, cytochrome c, and dATP.

Purification: Immunoaffinity purified

Immunogen: Peptide corresponding to aa 264-280 of the short form and aa 281-298 of the long form of human Livin.

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (2 - 4 μg/mL)

Usage: Western Blot: 2-4 μg/mL. In immunoblots, a band of 33 kD is detected. A weak band at 30 kD is detected in Raji cell lysate and probably represents the short form of human Livin.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for BIRC7

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Alternative Name: BIRC7 / Livin (BIRC7 Products)

Synonyms: KIAP antibody, LIVIN antibody, ML-IAP antibody, MLIAP antibody, RNF50 antibody, EIAP/XLX antibody, XLX antibody, kiap antibody, livin antibody, ml-iap antibody, mliap antibody, rnf50 antibody, xEIAP antibody, RGD1562883 antibody, zgc:165605 antibody, E130019N06 antibody, Livin antibody, birc7 antibody, bird7a antibody, xEIAP/XLX antibody, xlx antibody, EIAP/XLX-B antibody, birc7b antibody, baculoviral IAP repeat containing 7 antibody, baculoviral IAP repeat-containing 7 antibody, baculoviral IAP repeat-containing 7 (livin) antibody, baculoviral IAP repeat containing 7 S homeolog antibody, baculoviral IAP repeat containing 7 L homeolog antibody, BIRC7 antibody, birc7 antibody, Birc7 antibody, birc7.S antibody, birc7.L antibody

Background: Name/Gene ID: BIRC7
Family: Apoptosis

Synonyms: BIRC7, KIAP, Livin inhibitor of apoptosis, MLIAP, ML-IAP, RNF50, RING finger protein 50, LIVIN

Gene ID: 79444

UniProt: Q96CA5