MTA2 antibody (AA 652-668)
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- Target See all MTA2 Antibodies
- MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
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Binding Specificity
- AA 652-668
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MTA2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- Recognizes human, mouse, and rat PID/MTA2, a subunit of the nucleosome remodeling and deacetylating (NRD/NuRD) complex. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex, and its expression reduces the levels of acetylated p53. Deacetylation of p53 by PID/MTA2 represses p53- dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis. PID/MTA2 is expressed in a variety of tissues. Does not cross-react with MTA1.
- Purification
- Immunoaffinity purified
- Immunogen
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Peptide corresponding to aa 652-668 of human PID/MTA2. This sequence differs from that of mouse by one amino acid.
Type of Immunogen: Synthetic peptide - Top Product
- Discover our top product MTA2 Primary Antibody
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- Application Notes
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Approved: WB (0.5 - 1 μg/mL)
Usage: Western Blot: A band of 75 kD is detected. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C,-20 °C
- Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
- Alternative Name
- MTA2 (MTA2 Products)
- Synonyms
- MTA1L1 antibody, PID antibody, fd61b05 antibody, wu:fd61b05 antibody, wu:fi29g02 antibody, zgc:63487 antibody, pid antibody, mta1l1 antibody, MTA2 antibody, DKFZp470E0911 antibody, AW550797 antibody, Mata1l1 antibody, Mta1l1 antibody, mmta2 antibody, metastasis associated 1 family member 2 antibody, metastasis associated 1 family, member 2 antibody, metastasis-associated gene family, member 2 antibody, metastasis associated 1 family member 2 L homeolog antibody, MTA2 antibody, mta2 antibody, Mta2 antibody, mta2.L antibody
- Background
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Name/Gene ID: MTA2
Synonyms: MTA2, Metastasis-associated 1-like 1, MTA1L1, PID, MTA1-L1, MTA1-L1 protein - Gene ID
- 9219
- UniProt
- O94776
- Pathways
- Chromatin Binding
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