MAF antibody
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- Target See all MAF Antibodies
- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAF antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoelectron Microscopy (IEM)
- Specificity
- Reacts with human 47 kDa Maf protein derived from a transfected CEFcell line
- Purification
- Antiserum
- Immunogen
- Maf-GST fusion protein
- Isotype
- IgG
- Top Product
- Discover our top product MAF Primary Antibody
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- Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
-IHC : 1/50 to 1/500 - WB : 1/200 to 1/5 000 Useful for electrophoretic mobility shift assay (EMSA) - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Must be reconstituted in distilled water.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Expiry Date
- 24 months
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- Target
- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
- Alternative Name
- Transcription Factor Maf (MAF Products)
- Synonyms
- MAF antibody, DKFZp459D1731 antibody, 2810401A20Rik antibody, A230108G15Rik antibody, AW047063 antibody, c-maf antibody, CCA4 antibody, c-MAF antibody, Maf2 antibody, cMaf antibody, Z-cmaf antibody, c-Maf antibody, fl13d12 antibody, wu:fl13d12 antibody, C-Maf antibody, MAF bZIP transcription factor antibody, v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) antibody, avian musculoaponeurotic fibrosarcoma oncogene homolog antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a) antibody, MAF antibody, Maf antibody, mafa antibody
- Background
- Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element.
- NCBI Accession
- NP_001026974
- UniProt
- O75444
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