TMEM166 (FAM176A)
(Family with Sequence Similarity 176, Member A (FAM176A))
Reactivity
Human
Host
Sheep
Clonality
Polyclonal
Conjugate
This TMEM166 antibody is un-conjugated
Application
Western Blotting (WB), Immunohistochemistry (IHC)
Specificity
Specific for TMEM166.
Cross-Reactivity
Human, Mouse, Rat
Cross-Reactivity (Details)
Other species not yet tested.
Purification
IgG
Immunogen
A synthetic peptide from human transmembrane protein 166 (TM166, TMEM166) conjugated to blue carrier protein has been used as the antigen. The peptide is homologous in rat and mouse.
FAM176A
Reactivity: Human
WB, IF (p), IF (cc)
Host: Rabbit
Polyclonal
AbBy Fluor® 647
Application Notes
IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice
Avoid freeze and thaw cycles.
Storage
4 °C/-20 °C
Storage Comment
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months
Target
TMEM166 (FAM176A)
(Family with Sequence Similarity 176, Member A (FAM176A))
Fam176a antibody, RGD1559797 antibody, Tmem166 antibody, FAM176A antibody, TMEM166 antibody, BC014699 antibody, eva-1 homolog A, regulator of programmed cell death antibody, eva-1 homolog A (C. elegans) antibody, Eva1a antibody, EVA1A antibody
Background
FUNCTION: Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis. SUBCELLULAR LOCATION: Endoplasmic reticulum membrane, Single-pass membrane protein. Lysosome membrane, Single-pass membrane protein. TISSUE SPECIFICITY: Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.,Mammalian Autophagy,TM166, TMEM166