PAG1 antibody (AA 97-432)

Catalog No. ABIN351518

The Rabbit Polyclonal anti-PAG1 antibody is suitable to detect PAG1 in samples from Human and Mouse. It has been validated for WB, IP, IHC and IHC (p).

Quick Overview for PAG1 antibody (AA 97-432) (ABIN351518)

Target: PAG1 (phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PAG1 Antibody

Binding Specificity: AA 97-432

Specificity: Recognizes Csk-binding protein (Cbp / PAG), a 46 kD ubiquitously expressed transmembrane adaptor protein present in membrane rafts (glycosphingolipid-enriched microdomains), which however migrates on SDS PAGE gels anomalously as an 80 kD molecule.

Purification: Precipitation

Immunogen: Recombinant intracellular fragment (aa 97-432) of human Cbp (PAG).

Type of Immunogen: Recombinant protein

Application Details

Application Notes: Approved: IHC, IHC-P (10 μg/mL), IP, WB

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody,

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide, approx,  pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for PAG1

Target: PAG1 (phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))

Alternative Name: PAG1 / PAG

Background: Name/Gene ID: PAG1

Synonyms: PAG1, Csk-binding protein, CBP, PAG

Gene ID: 55824

UniProt: Q9NWQ8

Pathways: p53 Signaling, TCR Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events