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SWAP70 antibody (Middle Region)

SWAP70 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN356932
  • Target See all SWAP70 Antibodies
    SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))
    Binding Specificity
    • 15
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 58
    • 10
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 41
    • 16
    • 1
    Rabbit
    Clonality
    • 44
    • 14
    Polyclonal
    Conjugate
    • 31
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SWAP70 antibody is un-conjugated
    Application
    • 52
    • 27
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects SWAP70 at Center.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    KLH conjugated synthetic peptide selected from the center region of human SWAP70
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SWAP70 Primary Antibody
  • Application Notes
    ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target
    SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))
    Alternative Name
    SWAP70 (SWAP70 Products)
    Synonyms
    SWAP-70 antibody, 70kDa antibody, AV235546 antibody, HSPC321 antibody, swap70b antibody, zgc:63599 antibody, switching B-cell complex subunit SWAP70 antibody, SWA-70 protein antibody, SWAP switching B-cell complex 70 antibody, SWAP switching B-cell complex 70kDa subunit antibody, switching B-cell complex subunit SWAP70a antibody, SWAP70 antibody, Swap70 antibody, swap70 antibody, swap70a antibody
    Background
    SWAP70 is a phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. This protein regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.Synonyms: KIAA0640, SWAP-70, Switch-associated protein 70
    Molecular Weight
    68998 Da
    Gene ID
    23075, 9606
    UniProt
    Q9UH65
    Pathways
    Production of Molecular Mediator of Immune Response
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