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PKC gamma antibody (C-Term)

PRKCG Reactivity: Human, Mouse WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN359066
  • Target See all PKC gamma (PRKCG) Antibodies
    PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))
    Binding Specificity
    • 20
    • 15
    • 15
    • 14
    • 11
    • 9
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 107
    • 96
    • 68
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 143
    • 5
    • 1
    Rabbit
    Clonality
    • 128
    • 21
    Polyclonal
    Conjugate
    • 53
    • 15
    • 13
    • 9
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PKC gamma antibody is un-conjugated
    Application
    • 129
    • 59
    • 40
    • 39
    • 32
    • 18
    • 12
    • 8
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to PKC gamma.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PKC.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PRKCG Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))
    Alternative Name
    PRKCG (PRKCG Products)
    Synonyms
    PRKCG antibody, PKC-gamma antibody, PKCC antibody, PKCG antibody, SCA14 antibody, PKCgamma antibody, Pkcc antibody, Prkcc antibody, PKC antibody, PKCI antibody, Prkc antibody, RATPKCI antibody, protein kinase C gamma antibody, protein kinase C, gamma antibody, protein kinase C gamma type antibody, PRKCG antibody, Prkcg antibody, LOC484316 antibody
    Background
    Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC gamma is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).Synonyms: PKC gamma, PKC-gamma, PKCC, PKCG, Protein kinase C gamma type
    Gene ID
    5582, 9606
    UniProt
    P05129
    Pathways
    WNT Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGF Signaling
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