DCK antibody (C-Term)

Catalog No. ABIN359188

Product Details anti-DCK Antibody

Target: DCK (Deoxycytidine Kinase (DCK))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCK antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to DCK.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human DCK.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunoprecipitation: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for DCK

Target: DCK (Deoxycytidine Kinase (DCK))

Alternative Name: Deoxycytidine Kinase (DCK Products)

Synonyms: dck antibody, DCK antibody, wu:fc15f06 antibody, zgc:101771 antibody, dck1 antibody, deoxycytidine kinase antibody, deoxycytidine kinase, gene 2 L homeolog antibody, deoxycytidine kinase, gene 2 antibody, Deoxycytidine kinase antibody, deoxycytidine kinase, gene 1 L homeolog antibody, DCK antibody, dck antibody, dck.2.L antibody, dck.2 antibody, Dck antibody, FPV059 antibody, FPV151 antibody, dck.1.L antibody

Background: Deoxycytidine kinase is responsible for the phosphorylation of several deoxyribonucleosides and their analogs. Deficiency of this enzyme activity is associated with resistance to antiviral and anticancer chemotherapeutic agents, whereas increased enzyme activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. It is the rate limiting enzyme in the activation of many important anticancer and retroviral drugs and its activity is often decreased in cells that are resistant to cytosine arabinoside.Synonyms: DCK, MGC117410, MGC138632

Gene ID: 1633, 9606

UniProt: P27707