CLK1 antibody (N-Term)

Catalog No. ABIN359675

Product Details anti-CLK1 Antibody

Target: CLK1 (CDC like Kinase 1 (CLK1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLK1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes CLK1.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CLK1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for CLK1

Target: CLK1 (CDC like Kinase 1 (CLK1))

Alternative Name: CLK1 (CLK1 Products)

Synonyms: CLK antibody, CLK/STY antibody, STY antibody, CDC like kinase 1 antibody, CDC-like kinase 1 antibody, CLK1 antibody, Clk1 antibody

Background: This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection.Synonyms: CDC-like kinase 1, CLK, Dual specificity protein kinase CLK1

Molecular Weight: 57205 Da

Gene ID: 1195, 5874

UniProt: P49759