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EPS8 antibody (N-Term)

EPS8 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN360658
  • Target See all EPS8 Antibodies
    EPS8 (Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8))
    Binding Specificity
    • 15
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 47
    • 22
    • 10
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 46
    • 2
    • 1
    Rabbit
    Clonality
    • 49
    Polyclonal
    Conjugate
    • 21
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPS8 antibody is un-conjugated
    Application
    • 29
    • 21
    • 19
    • 13
    • 13
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to EPS8.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human EPS8.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product EPS8 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    EPS8 (Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8))
    Alternative Name
    EPS8 (EPS8 Products)
    Synonyms
    AW261790 antibody, MGC81285 antibody, MGC146320 antibody, zgc:56041 antibody, epidermal growth factor receptor pathway substrate 8 antibody, epidermal growth factor receptor pathway substrate 8 L homeolog antibody, EPS8 antibody, Eps8 antibody, eps8.L antibody, eps8 antibody
    Background
    Upon binding to EGF receptor, EPS8 enhances EGF-dependent mitogenic signals. It can bind multiple cellular targets. EPS8 is expressed in all tissues analyzed, including heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. It is expressed in all epithelial and fibroblastic lines examined and in some, but not all, hematopoietic cells. EPS8 is phosphorylated by several receptor tyrosine kinases. The protein contains 1 PH domain and 1 SH3 domain.Synonyms: Epidermal growth factor receptor kinase substrate 8
    Gene ID
    2059, 9606
    UniProt
    Q12929
    Pathways
    EGFR Signaling Pathway, Regulation of Actin Filament Polymerization
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