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CTNNA1 antibody (pSer641)
CTNNA1
Reactivity: Human, Mouse
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CTNNA1 Antibody
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Target
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CTNNA1
(Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))
Binding Specificity
All epitopes for CTNNA1 antibodies
pSer641
Reactivity
All reactivities for CTNNA1 antibodies
Human, Mouse
Host
All hosts for CTNNA1 antibodies
Rabbit
Clonality
All clonalities for CTNNA1 antibodies
Polyclonal
Conjugate
All conjugates for CTNNA1 antibodies
This CTNNA1 antibody is un-conjugated
Application
All applications for CTNNA1 antibodies
Western Blotting (WB)
Specificity
The antibody detects endogenous level of a-catenin only when phosphorylated at serine 641.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Immunogen
Peptide sequence around phosphorylation site of pSer641 (D-D-S (p) -D-F) derived from Human a-catenin. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
Isotype
IgG
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Application Details
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Application Notes
Western blotting: 1:500-1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for CTNNA1
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Target
CTNNA1
(Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))
Alternative Name
alpha-catenin (CTNNA1 Products )
Synonyms
CAP102 antibody, 2010010M04Rik antibody, AA517462 antibody, AI988031 antibody, Catna1 antibody, CG17947 antibody, CT39986 antibody, Dalpha-Cat antibody, Dalpha-cat antibody, DalphaC antibody, Dalphacat antibody, Dmcatp antibody, Dmel\\CG17947 antibody, a-Cat antibody, a-cat antibody, alpha-CAT antibody, alpha-cat antibody, alpha-catenin antibody, alpha-ctn antibody, alphaCAT antibody, alphaCat antibody, alphacat antibody, Alpha-Cat antibody, dgri_GLEANR_3829 antibody, DgriGH19548 antibody, GH19548 antibody, ctnna antibody, cap102 antibody, catna1 antibody, ctnna1 antibody, catenin alpha 1 antibody, catenin (cadherin associated protein), alpha 1 antibody, alpha Catenin antibody, catenin alpha-1 antibody, catenin (cadherin-associated protein), alpha 1 antibody, catenin alpha 1 S homeolog antibody, CTNNA1 antibody, Ctnna1 antibody, alpha-Cat antibody, Dgri\alpha-Cat antibody, Tsp_10127 antibody, ctnna1 antibody, ctnna1.S antibody
Background
Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. May play a crucial role in cell differentiation.
Molecular Weight
100 kDa
NCBI Accession
NP_001894
UniProt
P35221
Pathways
Regulation of Muscle Cell Differentiation , Cell-Cell Junction Organization , Maintenance of Protein Location
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