MAP1LC3A antibody (N-Term)
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- Target See all MAP1LC3A Antibodies
- MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
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Binding Specificity
- AA 1-100, N-Term
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Reactivity
- Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Bacteria
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAP1LC3A antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)
- Specificity
- Reacts withLC3 from human, mouse, rat, bacteria, golden syrian hamster, porcine and zebrafish
- Purification
- Antigen affinity purified
- Immunogen
- Synthetic peptide made to an N-terminal portion of the human LC3 protein sequence (between residues 1-100)
- Top Product
- Discover our top product MAP1LC3A Primary Antibody
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- Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB0.5-2 μg/mL ICC/IF1:200 IHC1:200-1:400 IP20 μg/500 μg of protein - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Tris-glycine, 150 mM NaCl, Sodium azide 0.05 %
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C/-80 °C
- Storage Comment
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- Target
- MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
- Alternative Name
- Light Chain 3 (LC3) (MAP1LC3A Products)
- Synonyms
- ATG8E antibody, LC3 antibody, LC3A antibody, MAP1ALC3 antibody, MAP1BLC3 antibody, 1010001H21Rik antibody, 4922501H04Rik antibody, LC3a antibody, MGC69006 antibody, zgc:77094 antibody, MGC89867 antibody, MAP1LC3A antibody, map1lc3a antibody, microtubule associated protein 1 light chain 3 alpha antibody, microtubule-associated protein 1 light chain 3 alpha antibody, microtubule associated protein 1 light chain 3 alpha S homeolog antibody, MAP1LC3A antibody, Map1lc3a antibody, map1lc3a.S antibody, map1lc3a antibody
- Background
- Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
- Gene ID
- 81631
- Pathways
- Autophagy
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