FXR1 antibody (Internal Region)

Catalog No. ABIN374719

Product Details anti-FXR1 Antibody

Target: FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This FXR1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: C-RIEGDNENKL PRED

Specificity: This antibody is expected to recognise all reported isoforms (NP_005078.2, NP_001013456.1 and NP_001013457.1).

Cross-Reactivity (Details): Species reactivity (expected):Human, Rat, Canine.
Species reactivity (tested):Mouse.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence Genename: FXR1

Application Details

Application Notes: ELISA: 1/128000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FXR1

Target: FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))

Alternative Name: FXR1 (FXR1 Products)

Synonyms: FXR1P antibody, wu:fb16f11 antibody, wu:fd18c10 antibody, zgc:66226 antibody, Fxr1h antibody, Fxr1p antibody, XtFxr1p antibody, fxr1h antibody, xFxr1p antibody, FXR1 antibody, 1110050J02Rik antibody, 9530073J07Rik antibody, AI851072 antibody, xfxr1 antibody, fxr1 antibody, FMR1 autosomal homolog 1 antibody, fragile X mental retardation, autosomal homolog 1 antibody, fragile X mental retardation gene 1, autosomal homolog antibody, FMR1 autosomal homolog 1 L homeolog antibody, FMR1 autosomal homolog 1 S homeolog antibody, FXR1 antibody, fxr1 antibody, Fxr1 antibody, fxr1.L antibody, fxr1.S antibody

Background: FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.Synonyms: Fragile X mental retardation syndrome-related protein 1, hFXR1p

Gene ID: 8087

NCBI Accession: NP_001013456

UniProt: P51114